产品货号：
GS4663
中文名称：
重组人Endostatin
英文名称：
Recombinant Human Endostatin
产品规格：
20μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 19.8kDa,a single non-glycosylated polypeptide chain containing 177 amino acids(C-terminal fragment of collagen XVIII).
储存条件：冷冻（-20℃）
概述
Endostatin has been identified as a C-terminal fragment of Collagen type 18,a recently identified member of a family of collagen-like proteins referred to as multiplexin family.Endostatin specifically inhibits proliferation of endothelial cells although it does not affect the proliferation of EOMA cells.Endostatin also potently inhibits angiogenesis and tumor growth.Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization.Endostatin can be found in vessel walls(elastic fibers)and basement membranes.Recombinant Endosatin expressed in yeast causes G1 arrest of endothelial cells,and endostatin treatment results in apoptosis of HUVE and HMVE cells.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人Endostatin，Endostatin, Human，Recombinant Human Endostatin
储存条件：冷冻（-20℃）
概述
Endostatin has been identified as a C-terminal fragment of Collagen type 18,a recently identified member of a family of collagen-like proteins referred to as multiplexin family.Endostatin specifically inhibits proliferation of endothelial cells although it does not affect the proliferation of EOMA cells.Endostatin also potently inhibits angiogenesis and tumor growth.Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization.Endostatin can be found in vessel walls(elastic fibers)and basement membranes.Recombinant Endosatin expressed in yeast causes G1 arrest of endothelial cells,and endostatin treatment results in apoptosis of HUVE and HMVE cells.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞96%by SDS-PAGE and HPLC analyses. |
| 来源 | Pichia Pastoris |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by inhibiting the FGF basic-dependent proliferation of HUVEC migration is less than 2.0μg/mL in the presence of Anti-Human Endostatin Polyclonal Antibody. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rHuEndostatin as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | NYEKPALHLA ALNMPFSGDI RADFQCFKQA RAAGLLSTYR AFLSSHLQDL STIVRKAERY SLPIVNLKGQ VLFNNWDSIF SGHGGQFNMH IPIYSFDGRD IMTDPSWPQK VIWHGSSPHG VRLVDNYCEA WRTADTAVTG LASPLSTGKI LDQKAYSCAN RLIVLCIENS FMTDARK |
相关搜索：重组人Endostatin，Endostatin, Human，Recombinant Human Endostatin